Orthopaedic Nurses Certification Board (ONCB) Metabolic/Inflammatory/Tumors Practice Exam

For what main condition is alendronate (Fosamax®) prescribed?

1. Hyperparathyroidism

2. Osteoporosis

3. Paget's disease

4. Hypercalcemia

The correct answer is: Osteoporosis

Alendronate, commonly known by its brand name Fosamax®, is primarily prescribed for the treatment and prevention of osteoporosis. Osteoporosis is a condition characterized by weakened bones that are more susceptible to fractures. The medication works by inhibiting bone resorption, which is the process whereby bone is broken down and the minerals released into the bloodstream. By slowing down this process, alendronate helps to maintain or increase bone density, thereby reducing the risk of fractures in individuals, particularly postmenopausal women and older adults who are at higher risk of developing osteoporosis. Although alendronate may have applications in other conditions, such as Paget's disease or hyperparathyroidism, its most common and primary use is in managing osteoporosis. The other options, such as hypercalcemia, refer to elevated calcium levels in the blood and do not relate directly to the mechanism of alendronate, which targets bone density and structure rather than calcium levels alone.